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MicroRNA-21 promotes the ovarian teratocarcinoma PA1 cell line by sustaining cancer stem/progenitor populations in vitro

INTRODUCTION: Resistance of cancer stem/progenitor cells (CSPCs) to chemotherapy can lead to cancer relapse. Ovarian teratocarcinoma (OVTC) arises from germ cells and comprises pluripotent cells that can be used to study cancer cell stemness. In this study, we evaluated whether microRNA-21 (miR-21)...

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Detalles Bibliográficos
Autores principales: Chung, Wei-Min, Chang, Wei-Chun, Chen, Lumin, Chang, Ying-Yi, Shyr, Chih-Rong, Hung, Yao-Ching, Ma, Wen-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854706/
https://www.ncbi.nlm.nih.gov/pubmed/23890123
http://dx.doi.org/10.1186/scrt247