Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model

INTRODUCTION: Cell therapy is a potential therapeutic approach for neurodegenerative disorders, such as Alzheimer disease (AD). Neuronal differentiation of stem cells before transplantation is a promising procedure for cell therapy. However, the therapeutic impact and mechanisms of action of neuron-...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Xie, ZhaoHong, Wei, LiFei, Yang, HongNa, Yang, ShaoNan, Zhu, ZhengYu, Wang, Ping, Zhao, CuiPing, Bi, JianZhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854736/
https://www.ncbi.nlm.nih.gov/pubmed/23826983
http://dx.doi.org/10.1186/scrt227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854736/
https://www.ncbi.nlm.nih.gov/pubmed/23826983
http://dx.doi.org/10.1186/scrt227

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