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Protein-Protein Interactions in a Crowded Environment: An Analysis via Cross-Docking Simulations and Evolutionary Information

Large-scale analyses of protein-protein interactions based on coarse-grain molecular docking simulations and binding site predictions resulting from evolutionary sequence analysis, are possible and realizable on hundreds of proteins with variate structures and interfaces. We demonstrated this on the...

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Detalles Bibliográficos
Autores principales: Lopes, Anne, Sacquin-Mora, Sophie, Dimitrova, Viktoriya, Laine, Elodie, Ponty, Yann, Carbone, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854762/
https://www.ncbi.nlm.nih.gov/pubmed/24339765
http://dx.doi.org/10.1371/journal.pcbi.1003369