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Further characterisation of rotavirus cores: Ss(+)RNAs can be packaged in vitro but packaging lacks sequence specificity()
Rotavirus (RV) cores were released from double-layered particles (DLPs) by high concentrations of CaCl(2), purified and ‘opened’ by treatment with EDTA or EGTA. Under appropriate in vitro conditions DLPs have been shown to have transcriptase and ‘open cores’ replicase activity. Furthermore, it has b...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854842/ https://www.ncbi.nlm.nih.gov/pubmed/24091366 http://dx.doi.org/10.1016/j.virusres.2013.09.034 |