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Over-Expression of 60s Ribosomal L23a Is Associated with Cellular Proliferation in SAG Resistant Clinical Isolates of Leishmania donovani

BACKGROUND: Sodium antimony gluconate (SAG) unresponsiveness of Leishmania donovani (Ld) had effectively compromised the chemotherapeutic potential of SAG. 60s ribosomal L23a (60sRL23a), identified as one of the over-expressed protein in different resistant strains of L.donovani as observed with dif...

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Detalles Bibliográficos
Autores principales: Das, Sanchita, Shah, Priyanka, Baharia, Rajendra K., Tandon, Rati, Khare, Prashant, Sundar, Shyam, Sahasrabuddhe, Amogh A., Siddiqi, M. I., Dube, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855005/
https://www.ncbi.nlm.nih.gov/pubmed/24340105
http://dx.doi.org/10.1371/journal.pntd.0002527