Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments

GCs are highly effective in treating a wide range of inflammatory diseases but are limited in their ability to control neutrophilic lung inflammation in conditions such as COPD. Neutrophil apoptosis, a central feature of inflammation resolution, is delayed in response to microenvironmental cues, suc...

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Detalles Bibliográficos
Autores principales: Marwick, John A., Dorward, David A., Lucas, Christopher D., Jones, Katie O., Sheldrake, Tara A., Fox, Sarah, Ward, Carol, Murray, Joanna, Brittan, Mairi, Hirani, Nik, Duffin, Rodger, Dransfield, Ian, Haslett, Christopher, Rossi, Adriano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2013
Materias:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855024/
https://www.ncbi.nlm.nih.gov/pubmed/23964116
http://dx.doi.org/10.1189/jlb.0912462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855024/
https://www.ncbi.nlm.nih.gov/pubmed/23964116
http://dx.doi.org/10.1189/jlb.0912462

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