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Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments
GCs are highly effective in treating a wide range of inflammatory diseases but are limited in their ability to control neutrophilic lung inflammation in conditions such as COPD. Neutrophil apoptosis, a central feature of inflammation resolution, is delayed in response to microenvironmental cues, suc...
Autores principales: | Marwick, John A., Dorward, David A., Lucas, Christopher D., Jones, Katie O., Sheldrake, Tara A., Fox, Sarah, Ward, Carol, Murray, Joanna, Brittan, Mairi, Hirani, Nik, Duffin, Rodger, Dransfield, Ian, Haslett, Christopher, Rossi, Adriano G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Leukocyte Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855024/ https://www.ncbi.nlm.nih.gov/pubmed/23964116 http://dx.doi.org/10.1189/jlb.0912462 |
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