Mice Deficient in Sfrp1 Exhibit Increased Adiposity, Dysregulated Glucose Metabolism, and Enhanced Macrophage Infiltration

The molecular mechanisms involved in the development of obesity and related complications remain unclear. Wnt signaling plays an important role in preadipocyte differentiation and adipogenesis. The expression of a Wnt antagonist, secreted frizzled related protein 1 (SFRP1), is increased in response...

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Detalles Bibliográficos
Autores principales: Gauger, Kelly J., Bassa, Lotfi M., Henchey, Elizabeth M., Wyman, Josephine, Bentley, Brooke, Brown, Melissa, Shimono, Akihiko, Schneider, Sallie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855156/
https://www.ncbi.nlm.nih.gov/pubmed/24339864
http://dx.doi.org/10.1371/journal.pone.0078320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855156/
https://www.ncbi.nlm.nih.gov/pubmed/24339864
http://dx.doi.org/10.1371/journal.pone.0078320

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