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CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model
BACKGROUND AND AIMS: C/EBP homologous protein (CHOP) plays pro-apoptotic roles in the integrated stress response. Recently, a tumor suppressive role for CHOP was demonstrated in lung cancer via regulation of tumor metabolism. To explore the role of CHOP in hepatocarcinogenesis, we induced hepatocell...
| Autores principales: | , , , , , |
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| Format: | Online Artículo Texto |
| Jezik: | English |
| Izdano: |
Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855209/ https://www.ncbi.nlm.nih.gov/pubmed/24339898 http://dx.doi.org/10.1371/journal.pone.0081065 |