CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model

BACKGROUND AND AIMS: C/EBP homologous protein (CHOP) plays pro-apoptotic roles in the integrated stress response. Recently, a tumor suppressive role for CHOP was demonstrated in lung cancer via regulation of tumor metabolism. To explore the role of CHOP in hepatocarcinogenesis, we induced hepatocell...

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Detalles Bibliográficos
Autores principales: Scaiewicz, Viviana, Nahmias, Avital, Chung, Raymond T., Mueller, Tobias, Tirosh, Boaz, Shibolet, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855209/
https://www.ncbi.nlm.nih.gov/pubmed/24339898
http://dx.doi.org/10.1371/journal.pone.0081065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855209/
https://www.ncbi.nlm.nih.gov/pubmed/24339898
http://dx.doi.org/10.1371/journal.pone.0081065

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