Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

AIMS/HYPOTHESIS: Type 2 diabetes is characterised by progressive beta cell dysfunction, with changes in gene expression playing a crucial role in its development. MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression and therefore alterations in miRNA levels may be involved in th...

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Detalles Bibliográficos
Autores principales: Locke, J. M., da Silva Xavier, G., Dawe, H. R., Rutter, G. A., Harries, L. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855472/
https://www.ncbi.nlm.nih.gov/pubmed/24149837
http://dx.doi.org/10.1007/s00125-013-3089-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855472/
https://www.ncbi.nlm.nih.gov/pubmed/24149837
http://dx.doi.org/10.1007/s00125-013-3089-4

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