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A Dose–Response Study of Arsenic Exposure and Global Methylation of Peripheral Blood Mononuclear Cell DNA in Bangladeshi Adults

Background: Several studies employing cell culture and animal models have suggested that arsenic (As) exposure induces global DNA hypomethylation. However, As has been associated with global DNA hypermethylation in human study populations. We hypothesized that this discrepancy may reflect a nonlinea...

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Detalles Bibliográficos
Autores principales: Niedzwiecki, Megan M., Hall, Megan N., Liu, Xinhua, Oka, Julie, Harper, Kristin N., Slavkovich, Vesna, Ilievski, Vesna, Levy, Diane, van Geen, Alexander, Mey, Jacob L., Alam, Shafiul, Siddique, Abu B., Parvez, Faruque, Graziano, Joseph H., Gamble, Mary V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855504/
https://www.ncbi.nlm.nih.gov/pubmed/24013868
http://dx.doi.org/10.1289/ehp.1206421