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Disruption of Aryl Hydrocarbon Receptor Homeostatic Levels during Embryonic Stem Cell Differentiation Alters Expression of Homeobox Transcription Factors that Control Cardiomyogenesis

Background: The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates the expression of xenobiotic detoxification genes and is a critical mediator of gene–environment interactions. Many AHR target genes identified by genome-wide gene expression profiling have morp...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Chen, Jing, Ko, Chia-I, Fan, Yunxia, Carreira, Vinicius, Chen, Yinglei, Xia, Ying, Medvedovic, Mario, Puga, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855521/
https://www.ncbi.nlm.nih.gov/pubmed/24058054
http://dx.doi.org/10.1289/ehp.1307297