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Tentative Identification of the Second Substrate Binding Site in Arabidopsis Phytochelatin Synthase
Phytochelatin synthase (PCS) uses the substrates glutathione (GSH, γGlu-Cys-Gly) and a cadmium (Cd)-bound GSH (Cd∙GS(2)) to produce the shortest phytochelatin product (PC(2), (γGlu-Cys)(2)-Gly) through a ping-pong mechanism. The binding of the 2 substrates to the active site, particularly the second...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855540/ https://www.ncbi.nlm.nih.gov/pubmed/24340051 http://dx.doi.org/10.1371/journal.pone.0082675 |