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Brucella Induces an Unfolded Protein Response via TcpB That Supports Intracellular Replication in Macrophages

Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates both therapy and vaccine development. Currently, ho...

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Detalles Bibliográficos
Autores principales: Smith, Judith A., Khan, Mike, Magnani, Diogo D., Harms, Jerome S., Durward, Marina, Radhakrishnan, Girish K., Liu, Yi-Ping, Splitter, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855547/
https://www.ncbi.nlm.nih.gov/pubmed/24339776
http://dx.doi.org/10.1371/journal.ppat.1003785