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Brucella Induces an Unfolded Protein Response via TcpB That Supports Intracellular Replication in Macrophages
Brucella melitensis is a facultative intracellular bacterium that causes brucellosis, the most prevalent zoonosis worldwide. The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates both therapy and vaccine development. Currently, ho...
Autores principales: | Smith, Judith A., Khan, Mike, Magnani, Diogo D., Harms, Jerome S., Durward, Marina, Radhakrishnan, Girish K., Liu, Yi-Ping, Splitter, Gary A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855547/ https://www.ncbi.nlm.nih.gov/pubmed/24339776 http://dx.doi.org/10.1371/journal.ppat.1003785 |
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