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The TFPI-2 Derived Peptide EDC34 Improves Outcome of Gram-Negative Sepsis

Sepsis is characterized by a dysregulated host-pathogen response, leading to high cytokine levels, excessive coagulation and failure to eradicate invasive bacteria. Novel therapeutic strategies that address crucial pathogenetic steps during infection are urgently needed. Here, we describe novel bioa...

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Detalles Bibliográficos
Autores principales: Papareddy, Praveen, Kalle, Martina, Sørensen, Ole E., Malmsten, Martin, Mörgelin, Matthias, Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855554/
https://www.ncbi.nlm.nih.gov/pubmed/24339780
http://dx.doi.org/10.1371/journal.ppat.1003803