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The TFPI-2 Derived Peptide EDC34 Improves Outcome of Gram-Negative Sepsis
Sepsis is characterized by a dysregulated host-pathogen response, leading to high cytokine levels, excessive coagulation and failure to eradicate invasive bacteria. Novel therapeutic strategies that address crucial pathogenetic steps during infection are urgently needed. Here, we describe novel bioa...
Autores principales: | Papareddy, Praveen, Kalle, Martina, Sørensen, Ole E., Malmsten, Martin, Mörgelin, Matthias, Schmidtchen, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855554/ https://www.ncbi.nlm.nih.gov/pubmed/24339780 http://dx.doi.org/10.1371/journal.ppat.1003803 |
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