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Mycobacterial MazG Safeguards Genetic Stability via Housecleaning of 5-OH-dCTP

Generation of reactive oxygen species and reactive nitrogen species in phagocytes is an important innate immune response mechanism to eliminate microbial pathogens. It is known that deoxynucleotides (dNTPs), the precursor nucleotides to DNA synthesis, are one group of the significant targets for the...

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Detalles Bibliográficos
Autores principales: Lyu, Liang-Dong, Tang, Bi-Kui, Fan, Xiao-Yong, Ma, Hui, Zhao, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855555/
https://www.ncbi.nlm.nih.gov/pubmed/24339782
http://dx.doi.org/10.1371/journal.ppat.1003814