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High MUC2 Expression in Ovarian Cancer Is Inversely Associated with the M1/M2 Ratio of Tumor-Associated Macrophages and Patient Survival Time

Mucin 2 (MUC2) is a mucin molecule aberrantly expressed by ovarian cancer cells. Previous in vitro studies have indicated that MUC2 promotes cancer growth and metastasis through a tumor-associated macrophage (TAM)-dependent mechanism. However, this mechanism has never been linked to clinical oncolog...

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Detalles Bibliográficos
Autores principales: He, Yi-feng, Zhang, Mei-ying, Wu, Xin, Sun, Xiang-jun, Xu, Ting, He, Qi-zhi, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855613/
https://www.ncbi.nlm.nih.gov/pubmed/24324582
http://dx.doi.org/10.1371/journal.pone.0079769