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ADENO-ASSOCIATED VIRUS TYPE 6 IS RETROGRADELY TRANSPORTED IN THE NON-HUMAN PRIMATE BRAIN

We recently demonstrated that axonal transport of adeno-associated virus (AAV) is serotype-dependent. Thus, AAV2 is anterogradely transported (e.g., from cell bodies to nerve terminals) in both rat and non-human primate (NHP) brain. In contrast, AAV6 is retrogradely transported from terminals to neu...

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Detalles Bibliográficos
Autores principales: Sebastian, Waldy San, Samaranch, Lluis, Heller, Gregory, Kells, Adrian P., Bringas, John, Pivirotto, Phillip, Forsayeth, John, Bankiewicz, Krystof S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855617/
https://www.ncbi.nlm.nih.gov/pubmed/24067867
http://dx.doi.org/10.1038/gt.2013.48