Cargando…

ADENO-ASSOCIATED VIRUS TYPE 6 IS RETROGRADELY TRANSPORTED IN THE NON-HUMAN PRIMATE BRAIN

We recently demonstrated that axonal transport of adeno-associated virus (AAV) is serotype-dependent. Thus, AAV2 is anterogradely transported (e.g., from cell bodies to nerve terminals) in both rat and non-human primate (NHP) brain. In contrast, AAV6 is retrogradely transported from terminals to neu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sebastian, Waldy San, Samaranch, Lluis, Heller, Gregory, Kells, Adrian P., Bringas, John, Pivirotto, Phillip, Forsayeth, John, Bankiewicz, Krystof S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855617/ https://www.ncbi.nlm.nih.gov/pubmed/24067867 http://dx.doi.org/10.1038/gt.2013.48

Ejemplares similares

Axonal transport of adeno-associated viral vectors is serotype-dependent
por: Salegio, Ernesto A., et al.
Publicado: (2012)

Safety and tolerability of MRI-guided infusion of AAV2-hAADC into the mid-brain of nonhuman primate
por: Sebastian, Waldy San, et al.
Publicado: (2014)

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy
por: Salegio, Ernesto A., et al.
Publicado: (2014)

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington’s disease
por: Hadaczek, Piotr, et al.
Publicado: (2016)

MR-Guided Delivery of AAV2-BDNF into the Entorhinal Cortex of Non-Human Primates
por: Nagahara, Alan H., et al.
Publicado: (2018)

Depletion of AADC activity in caudate nucleus and putamen of Parkinson’s disease patients; implications for ongoing AAV2-AADC gene therapy trial
por: Ciesielska, Agnieszka, et al.
Publicado: (2017)

Axonal transport of AAV9 in nonhuman primate brain
por: Green, Foad, et al.
Publicado: (2016)

MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain
por: Samaranch, L, et al.
Publicado: (2017)

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates
por: Ohno, Kousaku, et al.
Publicado: (2018)

Evaluation of an AAV2-Based Rapamycin-Regulated Glial Cell Line-Derived Neurotrophic Factor (GDNF) Expression Vector System
por: Hadaczek, Piotr, et al.
Publicado: (2011)

Carbidopa-Based Modulation of the Functional Effect of the AAV2-hAADC Gene Therapy in 6-OHDA Lesioned Rats
por: Ciesielska, Agnieszka, et al.
Publicado: (2015)

Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors (RRV) in a rodent brain tumor model
por: Yin, Dali, et al.
Publicado: (2013)

Ultrasound-Enhanced Drug Transport and Distribution in the Brain
por: Liu, Ying, et al.
Publicado: (2010)

An Update on Gene Therapy Approaches for Parkinson’s Disease: Restoration of Dopaminergic Function
por: Van Laar, Amber D., et al.
Publicado: (2021)

PET 6-[(18)F]fluoro-L-m-tyrosine Studies of Dopaminergic Function in Human and Nonhuman Primates
por: Eberling, Jamie L., et al.
Publicado: (2008)

Automated Segmentation Tool for Brain Infusions
por: Rosenbluth, Kathryn Hammond, et al.
Publicado: (2013)

Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience
por: Grahn, Amy Y., et al.
Publicado: (2009)

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe‐affected non‐human primates by intracerebral lentiviral gene therapy
por: Meneghini, Vasco, et al.
Publicado: (2016)

Efficient and Precise Processing of the Optimized Primary Artificial MicroRNA in a Huntingtin-Lowering Adeno-Associated Viral Gene Therapy In Vitro and in Mice and Nonhuman Primates
por: Wang, Wei, et al.
Publicado: (2022)

Retrograde capabilities of adeno-associated virus vectors in the central nervous system
por: Surdyka, Magdalena M., et al.
Publicado: (2021)

Gene Delivery to Nonhuman Primate Preimplantation Embryos Using Recombinant Adeno‐Associated Virus
por: Wang, Dan, et al.
Publicado: (2019)

The Use of Convection-Enhanced Delivery with Liposomal Toxins in Neurooncology
por: Fiandaca, Massimo S., et al.
Publicado: (2011)

Magnetic resonance imaging–guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease
por: Christine, Chadwick W., et al.
Publicado: (2019)

Gene Therapy for the Treatment of Parkinson’s Disease: The Nature of the Biologics Expands the Future Indications
por: Fiandaca, Massimo S., et al.
Publicado: (2012)

The tyrosine capsid mutations on retrograde adeno-associated virus accelerates gene transduction efficiency
por: Nakahama, Ryota, et al.
Publicado: (2022)

In utero recombinant adeno-associated virus gene transfer in mice, rats, and primates
por: Garrett, Deiadra J, et al.
Publicado: (2003)

Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity
por: Luz, Matthias, et al.
Publicado: (2018)

Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease
por: Richardson, R Mark, et al.
Publicado: (2020)

Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
por: Chuapoco, Miguel R., et al.
Publicado: (2023)

Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10
por: Milligan, Erin D, et al.
Publicado: (2005)

Adeno-Associated Virus-Mediated Gene Transfer to Renal Tubule Cells via a Retrograde Ureteral Approach
por: Chung, Daniel C., et al.
Publicado: (2011)

GDNF synthesis, signaling, and retrograde transport in motor neurons
por: Cintrón-Colón, Alberto F., et al.
Publicado: (2020)

A retrograde adeno-associated virus for collecting ribosome-bound mRNA from anatomically defined projection neurons
por: Cook-Snyder, Denise R., et al.
Publicado: (2015)

Adeno-Associated Viral Vector-Mediated Transgene Expression Is Independent of DNA Methylation in Primate Liver and Skeletal Muscle
por: Léger, Adrien, et al.
Publicado: (2011)

A COG in the retrograde transport machinery
por: Short, Ben
Publicado: (2011)

Adeno-Viren
por: Falke, Dietrich
Publicado: (2009)

Ganglioside Metabolism and Parkinson's Disease
por: Forsayeth, John, et al.
Publicado: (2018)

Convection-Enhanced Delivery of AAV2-PrPshRNA in Prion-Infected Mice
por: Ahn, Misol, et al.
Publicado: (2014)

Gene therapy for aromatic L-amino acid decarboxylase deficiency by MR-guided direct delivery of AAV2-AADC to midbrain dopaminergic neurons
por: Pearson, Toni S., et al.
Publicado: (2021)

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates
por: Rodríguez-Bocanegra, Eduardo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_btmiceoa5kecauk2f6u40bqbv0