Cargando…

Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Human autosomal recessive polycystic kidney disease (ARPKD) produces kidneys which are massively enlarged due to multiple cysts, hypertension, and congenital hepatic fibrosis characterized by dilated bile ducts and portal hypertension. The PCK rat is an orthologous model of human ARPKD with numerous...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshihara, Daisuke, Kugita, Masanori, Sasaki, Mai, Horie, Shigeo, Nakanishi, Koichi, Abe, Takaaki, Aukema, Harold M., Yamaguchi, Tamio, Nagao, Shizuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855683/
https://www.ncbi.nlm.nih.gov/pubmed/24324698
http://dx.doi.org/10.1371/journal.pone.0081480