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MCPIP1 Deficiency in Mice Results in Severe Anemia Related to Autoimmune Mechanisms

Autoimmune gastritis is an organ-specific autoimmune disease of the stomach associated with pernicious anemia. The previous work from us and other groups identified MCPIP1 as an essential factor controlling inflammation and immune homeostasis. MCPIP1(-/-) developed severe anemia. However, the mechan...

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Detalles Bibliográficos
Autores principales: Zhou, Zhou, Miao, Ruidong, Huang, Shengping, Elder, Brandon, Quinn, Tim, Papasian, Christopher J., Zhang, Jifeng, Fan, Daping, Chen, Y. Eugene, Fu, Mingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855756/
https://www.ncbi.nlm.nih.gov/pubmed/24324805
http://dx.doi.org/10.1371/journal.pone.0082542