Oct4/Sox2 Binding Sites Contribute to Maintaining Hypomethylation of the Maternal Igf2/H19 Imprinting Control Region

A central question in genomic imprinting is how parental-specific DNA methylation of imprinting control regions (ICR) is established during gametogenesis and maintained after fertilization. At the imprinted Igf2/H19 locus, CTCF binding maintains the unmethylated state of the maternal ICR after the b...

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Detalles Bibliográficos
Autores principales: Zimmerman, David L., Boddy, Craig S., Schoenherr, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855764/
https://www.ncbi.nlm.nih.gov/pubmed/24324735
http://dx.doi.org/10.1371/journal.pone.0081962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855764/
https://www.ncbi.nlm.nih.gov/pubmed/24324735
http://dx.doi.org/10.1371/journal.pone.0081962

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