Microarray and Morphological Analysis of Early Postnatal CRB2 Mutant Retinas on a Pure C57BL/6J Genetic Background

In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The severity of the phenotype due to human CRB1 or mouse Crb1 mutations is dependent on the genetic background. Mice on C57BL/6J background with C...

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Detalles Bibliográficos
Autores principales: Alves, Celso Henrique, Bossers, Koen, Vos, Rogier M., Essing, Anke H. W., Swagemakers, Sigrid, van der Spek, Peter J., Verhaagen, Joost, Wijnholds, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855766/
https://www.ncbi.nlm.nih.gov/pubmed/24324803
http://dx.doi.org/10.1371/journal.pone.0082532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855766/
https://www.ncbi.nlm.nih.gov/pubmed/24324803
http://dx.doi.org/10.1371/journal.pone.0082532

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