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Selective Vulnerability of Spinal and Cortical Motor Neuron Subpopulations in delta7 SMA Mice

Loss of the survival motor neuron gene (SMN1) is responsible for spinal muscular atrophy (SMA), the most common inherited cause of infant mortality. Even though the SMA phenotype is traditionally considered as related to spinal motor neuron loss, it remains debated whether the specific targeting of...

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Detalles Bibliográficos
Autores principales: d’Errico, Paolo, Boido, Marina, Piras, Antonio, Valsecchi, Valeria, De Amicis, Elena, Locatelli, Denise, Capra, Silvia, Vagni, Francesco, Vercelli, Alessandro, Battaglia, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855775/
https://www.ncbi.nlm.nih.gov/pubmed/24324819
http://dx.doi.org/10.1371/journal.pone.0082654