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Characterisation of Age-Dependent Beta Cell Dynamics in the Male db/db Mice

AIM: To characterise changes in pancreatic beta cell mass during the development of diabetes in untreated male C57BLKS/J db/db mice. METHODS: Blood samples were collected from a total of 72 untreated male db/db mice aged 5, 6, 8, 10, 12, 14, 18, 24 and 34 weeks, for measurement of terminal blood glu...

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Detalles Bibliográficos
Autores principales: Dalbøge, Louise S., Almholt, Dorthe L. C., Neerup, Trine S. R., Vassiliadis, Efstathios, Vrang, Niels, Pedersen, Lars, Fosgerau, Keld, Jelsing, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855780/
https://www.ncbi.nlm.nih.gov/pubmed/24324833
http://dx.doi.org/10.1371/journal.pone.0082813