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Moderate Hypoxia Followed by Reoxygenation Results in Blood-Brain Barrier Breakdown via Oxidative Stress-Dependent Tight-Junction Protein Disruption

Re-canalization of cerebral vessels in ischemic stroke is pivotal to rescue dysfunctional brain areas that are exposed to moderate hypoxia within the penumbra from irreversible cell death. Goal of the present study was to evaluate the effect of moderate hypoxia followed by reoxygenation (MHR) on the...

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Detalles Bibliográficos
Autores principales: Zehendner, Christoph M., Librizzi, Laura, Hedrich, Jana, Bauer, Nina M., Angamo, Eskedar A., de Curtis, Marco, Luhmann, Heiko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855783/
https://www.ncbi.nlm.nih.gov/pubmed/24324834
http://dx.doi.org/10.1371/journal.pone.0082823