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Recombinant Expression and In Vitro Characterisation of Active Huwentoxin-IV

Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. It is a member of the inhibitory cystine knot (ICK) peptide family, characterised by a compact globular structure maintained by three intramolecular disulfide bonds. Here we describe a novel s...

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Detalles Bibliográficos
Autores principales: Sermadiras, Isabelle, Revell, Jefferson, Linley, John E., Sandercock, Alan, Ravn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855799/
https://www.ncbi.nlm.nih.gov/pubmed/24324842
http://dx.doi.org/10.1371/journal.pone.0083202