Cargando…
Recombinant Expression and In Vitro Characterisation of Active Huwentoxin-IV
Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. It is a member of the inhibitory cystine knot (ICK) peptide family, characterised by a compact globular structure maintained by three intramolecular disulfide bonds. Here we describe a novel s...
Autores principales: | Sermadiras, Isabelle, Revell, Jefferson, Linley, John E., Sandercock, Alan, Ravn, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855799/ https://www.ncbi.nlm.nih.gov/pubmed/24324842 http://dx.doi.org/10.1371/journal.pone.0083202 |
Ejemplares similares
-
Detection and identification of huwentoxin-IV interacting proteins by biotin-avidin chemistry combined with mass spectrometry
por: Yu, Hai, et al.
Publicado: (2014) -
Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7
por: Tzakoniati, Foteini, et al.
Publicado: (2020) -
Functional Expression of Spider Neurotoxic Peptide Huwentoxin-I in E. coli
por: Meng, Er, et al.
Publicado: (2011) -
Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel
por: Rong, Mingqiang, et al.
Publicado: (2013) -
The structure, dynamics and selectivity profile of a Na(V)1.7 potency-optimised huwentoxin-IV variant
por: Rahnama, Sassan, et al.
Publicado: (2017)