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Nod2 Activates NF-kB in CD4(+) T Cells but Its Expression Is Dispensable for T Cell-Induced Colitis
Although the etiology of Crohn's disease (CD) remains elusive this disease is characterized by T cell activation that leads to chronic inflammation and mucosal damage. A potential role for maladaptation between the intestinal microbiota and the mucosal immune response is suggested by the fact t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855837/ https://www.ncbi.nlm.nih.gov/pubmed/24324812 http://dx.doi.org/10.1371/journal.pone.0082623 |