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Nod2 Activates NF-kB in CD4(+) T Cells but Its Expression Is Dispensable for T Cell-Induced Colitis

Although the etiology of Crohn's disease (CD) remains elusive this disease is characterized by T cell activation that leads to chronic inflammation and mucosal damage. A potential role for maladaptation between the intestinal microbiota and the mucosal immune response is suggested by the fact t...

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Detalles Bibliográficos
Autores principales: Zanello, Galliano, Goethel, Ashleigh, Forster, Katharina, Geddes, Kaoru, Philpott, Dana J., Croitoru, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855837/
https://www.ncbi.nlm.nih.gov/pubmed/24324812
http://dx.doi.org/10.1371/journal.pone.0082623