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Mutation at Intronic Repeats of the Ataxia-Telangiectasia Mutated (ATM) Gene and ATM Protein Loss in Primary Gastric Cancer with Microsatellite Instability

Ataxia-telangiectasia mutated (ATM) is a Ser/Thr protein kinase that plays a critical role in DNA damage-induced signaling and initiation of cell cycle checkpoint signaling in response to DNA-damaging agents such as ionizing radiation. We have previously reported the ATM protein loss by immunohistoc...

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Detalles Bibliográficos
Autores principales: Kim, Hee Sung, Choi, Seung Im, Min, Hae Lim, Kim, Min A., Kim, Woo Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855840/
https://www.ncbi.nlm.nih.gov/pubmed/24324828
http://dx.doi.org/10.1371/journal.pone.0082769