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Modulatory Effect of 1,25-Dihydroxyvitamin D(3) on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A
Receptor activator of nuclear factor κB ligand (RANKL) plays a crucial role in the bone erosion of rheumatoid arthritis (RA) by prompting osteoclastogenesis. Considering that 1,25(OH)(2)D(3) has been suggested as a potent inducer of RANKL expression, it should clarify whether vitamin D supplement co...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855937/ https://www.ncbi.nlm.nih.gov/pubmed/24348674 http://dx.doi.org/10.1155/2013/160123 |