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Feature-Based Classification of Amino Acid Substitutions outside Conserved Functional Protein Domains

There are more than 500 amino acid substitutions in each human genome, and bioinformatics tools irreplaceably contribute to determination of their functional effects. We have developed feature-based algorithm for the detection of mutations outside conserved functional domains (CFDs) and compared its...

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Detalles Bibliográficos
Autores principales: Gemovic, Branislava, Perovic, Vladimir, Glisic, Sanja, Veljkovic, Nevena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855963/
https://www.ncbi.nlm.nih.gov/pubmed/24348198
http://dx.doi.org/10.1155/2013/948617