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Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging

The misfolding, aggregation, and tissue accumulation of proteins are common events in diverse chronic diseases, known as protein misfolding disorders. Many of these diseases are associated with aging, but the mechanism for this connection is unknown. Recent evidence has shown that the formation and...

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Detalles Bibliográficos
Autores principales: Cuanalo-Contreras, Karina, Mukherjee, Abhisek, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855986/
https://www.ncbi.nlm.nih.gov/pubmed/24348562
http://dx.doi.org/10.1155/2013/638083