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Role of Intracellular Ca(2+) and Na(+)/Ca(2+) Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury

The precise mechanisms underlying contrast-induced acute kidney injury (CI-AKI) are not well understood. Intracellular Ca(2+) overload is considered to be a key factor in CI-AKI. Voltage-dependent Ca(2+) channel (VDC) and Na(+)/Ca(2+) exchanger (NCX) system are the main pathways of intracellular Ca(...

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Detalles Bibliográficos
Autores principales: Yang, Dingping, Yang, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855990/
https://www.ncbi.nlm.nih.gov/pubmed/24350283
http://dx.doi.org/10.1155/2013/678456