Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells

Emerging evidence indicates important protective roles being played by autophagy in neurodegenerative disorders through clearance of aggregate-prone or mutant proteins. In the current study, we aimed to identify autophagy inducers from Chinese medicinal herbs as a potential neuroprotective agent tha...

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Detalles Bibliográficos
Autores principales: Wu, An-Guo, Wong, Vincent Kam-Wai, Xu, Su-Wei, Chan, Wai-Kit, Ng, Choi-In, Liu, Liang, Law, Betty Yuen-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856081/
https://www.ncbi.nlm.nih.gov/pubmed/24248062
http://dx.doi.org/10.3390/ijms141122618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856081/
https://www.ncbi.nlm.nih.gov/pubmed/24248062
http://dx.doi.org/10.3390/ijms141122618

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