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Small Molecule Binding, Docking, and Characterization of the Interaction between Pth1 and Peptidyl-tRNA

Bacterial Pth1 is essential for viability. Pth1 cleaves the ester bond between the peptide and nucleotide of peptidyl-tRNA generated from aborted translation, expression of mini-genes, and short ORFs. We have determined the shape of the Pth1:peptidyl-tRNA complex using small angle neutron scattering...

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Detalles Bibliográficos
Autores principales: Hames, Mary C., McFeeters, Hana, Holloway, W. Blake, Stanley, Christopher B., Urban, Volker S., McFeeters, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856088/
https://www.ncbi.nlm.nih.gov/pubmed/24256814
http://dx.doi.org/10.3390/ijms141122741