Genetic Variation near IRF8 is Associated with Serologic and Cytokine Profiles in Systemic Lupus Erythematosus and Multiple Sclerosis

Alleles of IRF8 are associated with susceptibility to both systemic lupus erythematosus (SLE) and multiple sclerosis (MS). While high type I interferon (IFN) is thought to be causal in SLE, type I IFN is used as a therapy in MS. We investigated whether IRF8 alleles were associated with type I IFN le...

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Detalles Bibliográficos
Autores principales: Chrabot, Beverly S., Kariuki, Silvia N., Zervou, Maria I., Feng, Xuan, Arrington, Jasmine, Jolly, Meenakshi, Boumpas, Dimitrios T., Reder, Anthony T., Goulielmos, George N., Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856198/
https://www.ncbi.nlm.nih.gov/pubmed/23965942
http://dx.doi.org/10.1038/gene.2013.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856198/
https://www.ncbi.nlm.nih.gov/pubmed/23965942
http://dx.doi.org/10.1038/gene.2013.42

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