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Optical Control of Mammalian Endogenous Transcription and Epigenetic States

The dynamic nature of gene expression enables cellular programming, homeostasis, and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene...

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Detalles Bibliográficos
Autores principales: Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro, Hsu, Patrick D., Heidenreich, Matthias, Cong, Le, Platt, Randall J., Scott, David A., Church, George M., Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856241/
https://www.ncbi.nlm.nih.gov/pubmed/23877069
http://dx.doi.org/10.1038/nature12466