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Optical Control of Mammalian Endogenous Transcription and Epigenetic States
The dynamic nature of gene expression enables cellular programming, homeostasis, and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of gene...
Autores principales: | Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro, Hsu, Patrick D., Heidenreich, Matthias, Cong, Le, Platt, Randall J., Scott, David A., Church, George M., Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856241/ https://www.ncbi.nlm.nih.gov/pubmed/23877069 http://dx.doi.org/10.1038/nature12466 |
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