Dynamic switching of calmodulin interactions underlies Ca(2+) regulation of Ca(V)1.3 channels

Calmodulin regulation of Ca(V) channels is a prominent Ca(2+) feedback mechanism orchestrating vital adjustments of Ca(2+) entry. The long-held structural correlate of this regulation has been Ca(2+)-bound calmodulin complexed alone with an IQ domain on the channel carboxy terminus. Here, however, s...

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Detalles Bibliográficos
Autores principales: Ben Johny, Manu, Yang, Philemon S., Bazzazi, Hojjat, Yue, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856249/
https://www.ncbi.nlm.nih.gov/pubmed/23591884
http://dx.doi.org/10.1038/ncomms2727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856249/
https://www.ncbi.nlm.nih.gov/pubmed/23591884
http://dx.doi.org/10.1038/ncomms2727

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