Self-assembled HCV core virus-like particles targeted and inhibited tumor cell migration and invasion

We used a baculovirus expression system to express fusion proteins of HCV core, RGD (Arg-Gly-Asp) peptide, and IFN-α2a fragments in Sf9 cells. Western blotting and electron microscopy demonstrate that HCV core, peptides RGD, and IFN-α2a fusion proteins assemble into 30 to 40 nm nano-particles (virus...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Xu, Xuehe, Jin, Aihui, Jia, Qunying, Zhou, Huaibin, Kang, Shuai, Lou, Yongliang, Gao, Jimin, Lu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856463/
https://www.ncbi.nlm.nih.gov/pubmed/24074276
http://dx.doi.org/10.1186/1556-276X-8-401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856463/
https://www.ncbi.nlm.nih.gov/pubmed/24074276
http://dx.doi.org/10.1186/1556-276X-8-401

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