MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma

BACKGROUND: microRNAs have been shown to regulate the chemosensitivity of cancer cells. The aim of this study is to investigate the role and mechanism of mir-23a in enhancing the anti-tumor effect of topoisomerase 2A (TOP2A) poison etoposide in human hepatocellular carcinoma (HCC). METHODS: The anti...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Zhu, Meifen, Tsao, Sai-Wah, Man, Kwan, Zhang, Zhangjin, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856574/
https://www.ncbi.nlm.nih.gov/pubmed/24103454
http://dx.doi.org/10.1186/1476-4598-12-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856574/
https://www.ncbi.nlm.nih.gov/pubmed/24103454
http://dx.doi.org/10.1186/1476-4598-12-119

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