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Development and validation of COMPASS: clinical evidence of orphan medicinal products – an assessment tool
BACKGROUND: Rare diseases are defined as life-threatening or chronically debilitating diseases with a prevalence of 50 out of 100,000 individuals or less. Orphan medicinal products (OMPs) are intended for the treatment of rare diseases. The assessment of quality of evidence in small populations is o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856624/ https://www.ncbi.nlm.nih.gov/pubmed/24107467 http://dx.doi.org/10.1186/1750-1172-8-157 |