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A review of post-GWAS prioritization approaches

In the recent decade, high-throughput genotyping and next-generation sequencing platforms have enabled genome-wide association studies (GWAS) of many complex human diseases. These studies have discovered many disease susceptible loci, and unveiled unexpected disease mechanisms. Despite these success...

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Detalles Bibliográficos
Autores principales: Hou, Lin, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856625/
https://www.ncbi.nlm.nih.gov/pubmed/24367376
http://dx.doi.org/10.3389/fgene.2013.00280