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Cis-Acting Regulation of Brain-Specific ANK3 Gene Expression by a Genetic Variant Associated with Bipolar Disorder

Several genome-wide association studies (GWAS) for bipolar disorder (BD) have found a strong association of the Ankyrin3 (ANK3) gene. This association spans numerous linked single nucleotide polymorphisms (SNPs) in a ~250 kb genomic region overlapping ANK3. The associated region encompasses predicte...

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Detalles Bibliográficos
Autores principales: Rueckert, Erroll H., Barker, Douglas, Ruderfer, Douglas, Bergen, Sarah E., O’Dushlaine, Colm, Luce, Catherine J., Sheridan, Steven D., Theriault, Kraig M., Chambert, Kimberly, Moran, Jennifer, Purcell, Shaun, Madison, Jon M., Haggarty, Stephen J., Sklar, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856665/
https://www.ncbi.nlm.nih.gov/pubmed/22850628
http://dx.doi.org/10.1038/mp.2012.104