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The contribution of TWIK-1 channels to astrocyte K(+) current is limited by retention in intracellular compartments

TWIK-1 two-pore domain K(+) channels are expressed abundantly in astrocytes. In the present study, we examined the extent to which TWIK-1 contributes to the linear current-voltage (I–V) relationship (passive) K(+) membrane conductance, a dominant electrophysiological feature of mature hippocampal as...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Putra, Adhytia, Schools, Gary P., Ma, Baofeng, Chen, Haijun, Kaczmarek, Leonard K., Barhanin, Jacques, Lesage, Florian, Zhou, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856854/
https://www.ncbi.nlm.nih.gov/pubmed/24368895
http://dx.doi.org/10.3389/fncel.2013.00246