Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats

We have reported that PEGylated liposomes lose their long-circulating properties when they are administered repeatedly at certain intervals to the same animal. This unexpected phenomenon is referred to as the accelerated blood clearance (ABC) phenomenon. We recently showed that the ABC phenomenon is...

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Detalles Bibliográficos
Autores principales: Ichihara, Masako, Shimizu, Taro, Imoto, Ami, Hashiguchi, Yuki, Uehara, Yumi, Ishida, Tatsuhiro, Kiwada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857034/
https://www.ncbi.nlm.nih.gov/pubmed/24310423
http://dx.doi.org/10.3390/pharmaceutics3010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857034/
https://www.ncbi.nlm.nih.gov/pubmed/24310423
http://dx.doi.org/10.3390/pharmaceutics3010001

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